Intact protein LC–MS for pharmacokinetics
نویسندگان
چکیده
منابع مشابه
CMS, LMS and LCMS For eLearning
Now a day’s most of the educational centre (universities, institutes, colleges and schools) are using some eLearning tools as an integral part of their learning systems; to enhance their traditional learning systems or to use an alternative approach for virtual learning environment. These tools may base on content management or learning content management. Recently a composition of Learning Man...
متن کاملLCMS-96_Identifying psychotropics using Toxtyper _2014.indd
Various instrument types and LC-MS approaches have been explored in an attempt to develop a comprehensive analysis method for detecting and definitely identifying as many compounds as possible in a single run. However, everyday analyses often require the detection of a defined set of substances (for example, hypnotics in cases of drugfacilitated assault (DFA). The aim of this project was to dev...
متن کاملTargeted, LCMS-based Metabolomics for Quantitative Measurement of NAD+ Metabolites
Nicotinamide adenine dinucleotide (NAD(+)) is a coenzyme for hydride transfer reactions and a substrate for sirtuins and other NAD(+)-consuming enzymes. The abundance of NAD (+), NAD(+) biosynthetic intermediates, and related nucleotides reflects the metabolic state of cells and tissues. High performance liquid chromatography (HPLC) followed by ultraviolet-visible (UV-Vis) spectroscopic analysi...
متن کاملMethods for L-ribooligonucleotide sequence determination using LCMS
The ability to verify the sequence of a nucleic acid-based therapeutic is an essential step in the drug development process. The challenge associated with sequence identification increases with the length and nuclease resistance of the nucleic acid molecule, the latter being an important attribute of therapeutic oligonucleotides. We describe methods for the sequence determination of Spiegelmers...
متن کاملBquant – Novel script for batch quantification of LCMS data
Quantitative target analysis by liquid chromatography coupled to mass spectrometry (LCMS) is ubiquitous in environmental, metabolomic and toxicological studies. Targeted LCMS methods are capable of the simultaneous determination of literally hundreds of analytes. Although acquiring of instrumental data is very fast, data post-processing i.e. quantification can be time consuming step (and)or dep...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Pharmacokinetics
سال: 2019
ISSN: 2053-0846,2053-0854
DOI: 10.4155/ipk-2020-0004